Cryogenic Mills
Cryogenic Mills are used to chill and pulverize samples to liquid nitrogen temperatures. The sample vial (0.5 - 4ml capacity) is immersed in liquid nitrogen throughout the grinding cycle. The sample is stabilized at cryogenic temperatures and its key characteristics preserved. 50ml sample capacity vials are available for use with the larger cryogenic mill. Other features provide for speed control (2 - 30 impacts/second) and programmable grinding duration (0.1 - 100 minutes).
The Cryogenic Mill maintains a vital role for biological discovery, pharmaceutical analysis, drug testing, medical research, forensic science and many other analytical investigations. Cryogenic grinding prepares any biological material for nucleic acid extraction without damaging the RNA or DNA. Skeletal material including human bones and teeth can be ground cryogenically and DNA extracted from the powder, whether the remains are recent or very old. Plant and animal tissue of all types is easily ground and the resultant sample material can be subjected to classical methods of RNA extraction and analysis. The complex molecules present in drugs such as isomers and their metabolites are critical to both pharmaceutical researchers and crime labs. Among endless possibilities in the medical field, many cases have pulverized fresh bone and used the growth matter to stimulate the formation of bone around prosthetic implants.
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