Difference between revisions of "Pharmaceutical Mills"
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[[File:Pharmaceutical Mills_1.jpg|thumb|200px|right|Pharmaceutical Mills]] | |||
[[File:Pharmaceutical Mills_2.jpg|thumb|200px|right|Pharmaceutical Mills]] | |||
'''Pharmaceutical Mills''' are size reduction mills that are used widely throughout the pharmaceutical industry for the reduction of active ingredients (API's), as well as bulk pharmaceuticals (BPI's) and excipients such as lactose, HPMC (hydroxypropylmethyl cellulose) and others. | |||
Size reduction in pharmaceutical processes is used to increase surface area and improve formulation dissolution properties. | |||
It is also used to maintain a consistent average particle size distribution (PSD) for the formulation, thus allowing for a better quality mixture when creating solid dosage forms such as tablets and capsules. | |||
==Typical Features== | |||
*All stainless steel construction, without the use of flexible liners which may abrade and wear due to cleaning cycles and detergents/ solvents used | |||
*Fully enclosed motor and gearbox, to ensure a clear separation between the “process” and technical area, thus preventing added cleaning concerns | |||
*Unique and fully purged shaft sealing arrangements to ensure no leakage of product into the bearing/seal area § All machined and polished construction, eliminating the use of cast constructions, thus removing any possible pits and crevices | |||
*All welds continuous and polished | |||
*Easy dismantling without the use of tools through the use of triclover clamps and connections | |||
*Options available for inerting, pressure compensations, glove box integrations, product isolations, rinse in place cleaning | |||
==Video== | |||
<youtube>I4E-Q2lVneY</youtube> | |||
Latest revision as of 23:32, 14 October 2012
Pharmaceutical Mills are size reduction mills that are used widely throughout the pharmaceutical industry for the reduction of active ingredients (API's), as well as bulk pharmaceuticals (BPI's) and excipients such as lactose, HPMC (hydroxypropylmethyl cellulose) and others.
Size reduction in pharmaceutical processes is used to increase surface area and improve formulation dissolution properties.
It is also used to maintain a consistent average particle size distribution (PSD) for the formulation, thus allowing for a better quality mixture when creating solid dosage forms such as tablets and capsules.
Typical Features
- All stainless steel construction, without the use of flexible liners which may abrade and wear due to cleaning cycles and detergents/ solvents used
- Fully enclosed motor and gearbox, to ensure a clear separation between the “process” and technical area, thus preventing added cleaning concerns
- Unique and fully purged shaft sealing arrangements to ensure no leakage of product into the bearing/seal area § All machined and polished construction, eliminating the use of cast constructions, thus removing any possible pits and crevices
- All welds continuous and polished
- Easy dismantling without the use of tools through the use of triclover clamps and connections
- Options available for inerting, pressure compensations, glove box integrations, product isolations, rinse in place cleaning
Video