Difference between revisions of "Lyophilizers"

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[[File:Lyophilizers.jpg|thumb|right|200px|Lyophilizers]]
The '''Lyophilizers''' are used especially for Lyophilization  process. It is a complex  process of removing water from the product through sublimation at low  temperature & vacuum. The equipment (often called '''Lyophilizers''') is a very difficult type of chamber to thermally map. A lyophilizer has  many  shelves that are closely spaced together to hold product.  Accurately measuring  the shelf temperature during the process cycle can  be quite challenging  particularly if using thermocouples.
 
 
Installation  of thermocouples  into a lyophilizer is very time intensive. Thermocouples must be  threaded into the chamber through the vacuum line using a special flange assembly. The tip of each thermocouple must be  carefully strapped or taped onto multiple positions of each shelf. If not done properly, the shelf  temperature measurements will not be  accurately mapped. Vacuum leaks and broken  thermocouples are common  problems which can add significantly to equipment  downtime.
             
Using  a thermocouple based system for this application should  be considered only if seeing live data is absolutely necessary. For '''Lyophilizers''' it is new and has never been qualified.  In this case, seeing live data may be advantageous to allow for mechanical adjustments or to determine product load configurations.
             
The  better alternative is to use wireless dataloggers that are designed to handle  this application. The Lives data of wireless dataloggers are ideally suited for mapping lyophilizers.  Each datalogger has an 18 inch extended sensor. A copper cap is  provided that  slips onto the bottom portion of each datalogger. The  copper cap has a groove so that the sensor can be flush mounted.  The datalogger can then be placed on any shelf location with the thermally insulated to the shelf temperature.
 
 
In  summary, the live data of wireless  dataloggers can save substantial hours of labor and equipment downtime  for this application. Also, periodic verifications of the  process conditions can be easily  done without disruption to operations.

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